Pengaruh Pemberian Kapsul Jintan Hitam terhadap Kadar Kolesterol Ibu Rumah Tangga

  • Bela Novita Amaris Susanto Universitas Yatsi Madani Tangerang
  • Nindita Clourisa Amaris Susanto Universitas Sebelas Maret
Keywords: High Density Lipoproteins; Total Cholesterol; Low Density Lipoproteins; Triglycerides; Degenerative Disease

Abstract

Along with increasing age, a person's health condition can decrease, thus making him susceptible to various kinds of degenerative diseases. One of the early metabolic syndromes for degenerative diseases is high cholesterol levels. Prevention can be done by consuming black cumin which has a lot of content and benefits. The purpose of this study was to determine the effect of consuming black cumin capsules on total cholesterol, low density lipoprotein, high density lipoprotein and triglyceride levels in housewives. Quasi experimental research with one group pre-test post-test approach. Samples were taken by purposive sampling technique, amounting to 20 housewives. The research was conducted from March to July 2022 in Tangerang City. Laboratory measurements were carried out before and after administration of black cumin capsules at a dose of 3x1 capsules per day. The data were analyzed using the paired sample t-test. The results showed that the p value for total cholesterol, low density lipoprotein, high density lipoprotein, and triglycerides was < 0.001 (p < 0.05). There is an effect of consuming black cumin capsules on decreasing total cholesterol, low density lipoprotein and triglyceride levels, and effect on increasing high density lipoprotein levels. It is hoped that black cumin capsules can be used as a companion or additional therapy in controlling cholesterol levels in the body.

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References

McPhee JS, French DP, Jackson D, Nazroo J, Pendleton N, Degens H. Physical activity in older age: perspectives for healthy ageing and frailty. Biogerontology. 2016;17(3):567–80.

Sani RA. Cara Membuat Soal AKM untuk SD dan SMP. 2021. 5–6 p.

Al-Rahmad AH, Annaria A, Fadjri TK. Faktor Resiko Peningkatan Kolesterol pada Usia Diatas 30 Tahun di Kota Banda Aceh. J Nutr. 2016;18(2):109–14.

Mulyani NS, Al Rahmad AH, Jannah R. Faktor resiko kadar kolesterol darah pada pasien rawat jalan penderita jantung koroner di RSUD Meuraxa. AcTion Aceh Nutr J. 2018;3(2):132.

Marlinda L. Efektivitas ekstrak etanol biji Jintan hitam (Nigella sativa Linn.) terhadap peningkatan fagositosis dalam respon imun tubuh. J Major. 2015;4:58–64.

Sharma MM. 30 Simple Ways to Manage Cholesterol. Diamond Pocket Books; 2016.

Darmawan AB. Anti-Aging Rahasia Tampil Muda di Segala Usia. Vol. 8, Yogyakarta: Media Press. Media Preesindo; 2013. 18–41 p.

Salem AM, Bamosa AO, Qutub HO, Gupta RK, Badar A, Elnour A, et al. Effect of Nigella sativa supplementation on lung function and inflammatory mediators in partly controlled asthma: A randomized controlled trial. Ann Saudi Med. 2017;37(1):64–71.

Junaedi, E., Sufrida, Y., Sumahika, S., & Emma SK. Kedahsyatan Habbatussauda Mengobati Berbagai Penyakit. e-Jurnal Pustaka Kesehat [Internet]. 2011; Available from: https://books.google.co.id/books?hl=id&lr=&id=ydKKypYmafgC&oi=fnd&pg=PA1&dq=info:q_iU01n-0RkJ:scholar.google.com/&ots=5tXOY8Tto_&sig=L9ZNxENUJaKOczU2-xwNCoO5NWU&redir_esc=y#v=onepage&q&f=false

Makmun A, Surdam Z, Gunawan AM. Uji Efektivitas Ekstrak Jintan Hitam (Nigella Sativa) Terhadap Pertumbuhan Bakteri Staphylococcus Aureus Pada Medium MHA (Mueller Hinton Agar). Wind Heal J Kesehat. 2020;1–9.

Taufiqurrahman. 3 Mutiara Kesehatan Alami yang Terlupakan. 2017. 12–13 p.

Anna LK. Meski Banyak Manfaatnya, Ketahui Juga Efek Samping Habbatussauda [Internet]. kompas.com. 2022. Available from: https://lifestyle.kompas.com/read/2021/02/28/165858220/meski-banyak-manfaatnya-ketahui-juga-efek-samping-habbatussauda?page=all

Saputri DA, Novitasari A. Hubungan Usia Dengan Kadar Kolesterol Masyarakat Di Kota Bandar Lampung. BIOEDUKASI (Jurnal Pendidik Biol. 2021;12(2):238.

Kemenkes RI. Berapa Nilai Normal Kolesterol Total? - Direktorat P2PTM [Internet]. Direktorat Pencegahan Dan Pengendalian Penyakit Tidak Menular. 2019. Available from: http://p2ptm.kemkes.go.id/infographic-p2ptm/hipertensi-penyakit-jantung-dan-pembuluh-darah/page/13/berapa-nilai-normal-kolesterol-total

Sari W, Indrawati L, Dewi CS. Stroke cegah dan obati sendiri. Penebar Swadaya Grup; 2016. 1–160 p.

Kooti W, Hasanzadeh-Noohi Z, Sharafi-Ahvazi N, Asadi-Samani M, Ashtary-Larky D. Phytochemistry, pharmacology, and therapeutic uses of black seed (Nigella sativa). Chin J Nat Med. 2016;14(10):732–45.

Amanulloh M, Krisdayanti E. Jintan Hitam sebagai Imunomodulator dan Anti Inflamasi pada Pasien Asma. J Penelit Perawat Prof. 2019;1(1):115–20.

Anggraini DI, Nabillah LF. Activity Test of Suji Leaf Extract (Dracaena angustifolia Roxb.) on in vitro cholesterol lowering. J Kim Sains dan Apl. 2018;21(2):54–8.

Bokelmann JM. Black Seed/Nigella/Black Cumin (Nigella sativa). Med Herbs Prim Care. 2022;235–52.

Rahim MA, Shoukat A, Khalid W, Ejaz A, Itrat N, Majeed I, et al. A Narrative Review on Various Oil Extraction Methods, Encapsulation Processes, Fatty Acid Profiles, Oxidative Stability, and Medicinal Properties of Black Seed (Nigella sativa). Foods. 2022;11(18).

Tim Redaksi Trubus. My Healthy Life: Trio Herbal. 2010;128.

Khairunnisa L, Ngestiningsih D, Setyawati AN. Pengaruh Pemberian Ekstrak Jintan Hitam (Nigella Sativa) Terhadap Kadar Mda Serum Tikus Sprague Dawley Setelah Diberikan Paparan Asap Rokok. Diponegoro Med J (Jurnal Kedokt Diponegoro). 2016;5(4):1171–81.

Wijaya R, Sastramihardja HS, Indriyanti RA. Pengaruh Pemberian Ekstrak Etanol Biji Jintan Hitam (Nigella sativa) terhadap Kadar Kolesterol Total Darah pada Mencit Model Hiperkolesterolemia. Pros Pendidik Dr. 2018;448–54.
Ahmad MF, Ahmad FA, Ashraf SA, Saad HH, Wahab S, Khan MI, et al. An updated knowledge of Black seed (Nigella sativa Linn.): Review of phytochemical constituents and pharmacological properties. J Herb Med. 2021;25.

Yuliana AR, Ardiaria M. Efek Pemberian Seduhan Kulit Buah Naga Merah Terhadap Kadar Kolesterol LDL (LOW DENSITY LIPOPROTEIN) Tikus SPRAGUE DAWLEY Dislipidemia. 2016;5(4):428–37.

Aydın B. A preliminary assessment of the effects of dietary black cumin seed cake on growth performance, serum biochemical parameters and fatty acid composition of mirror carp (Cyprinus carpio var. specularis) fingerlings. Aquac Reports. 2021;21.

Luo J, Yang H, Song BL. Mechanisms and regulation of cholesterol homeostasis. Nat Rev Mol Cell Biol. 2020;21(4):225–45.

Sahebkar A, Beccuti G, Simental-Mendía LE, Nobili V, Bo S. Nigella sativa (black seed) effects on plasma lipid concentrations in humans: A systematic review and meta-analysis of randomized placebo-controlled trials. Pharmacol Res. 2016;106:37–50.

Bamosa A, Lebda F, Al Elq A, Al-Sultan A, Kaatabi H. Favorable impact of Nigella sativa seeds on lipid profile in type 2 diabetic patients. J Fam Community Med. 2012;19(3):155.

Haas MJ, Naem E, Almdallaleh S, Mooradian AD. The effect of black seed (Nigella sativa) extract on lipid metabolism in HepG2 cells. Biochim Biophys Acta - Mol Cell Biol Lipids. 2022;1867(8).
Published
2023-06-14
How to Cite
Susanto, B., & Susanto, N. C. (2023). Pengaruh Pemberian Kapsul Jintan Hitam terhadap Kadar Kolesterol Ibu Rumah Tangga. Jurnal Sehat Mandiri, 18(1), 95-104. https://doi.org/https://doi.org/10.33761/jsm.v18i1.848